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  • Enoxaparin Sodium
    CAS No.: 679809-58-6 (Low molecular weight heparin)

    Short Description:

    Source: Extracted from porcine intestinal mucosa and degraded by β-elimination method.

    Function and use: By inhibiting coagulation active factor X (FXa) and thrombin (FIIa), heparin pentose structure binds AT-III (antithrombin III), and exerts anticoagulant effect.
    Enoxaparin sodium prevents venous thromboembolic disease (prevention of thrombosis in the veins), especially those associated with orthopaedic or general surgery; treats established deep vein thrombosis, with or without pulmonary embolism, clinical Symptoms are not severe, excluding pulmonary embolism requiring surgery or thrombolytic therapy; treatment of unstable angina pectoris and non-Q-wave myocardial infarction, in combination with aspirin; used in hemodialysis cardiopulmonary bypass to prevent thrombosis; treatment of acute ST segment Elevated myocardial infarction, combined with thrombolytics or concurrently with percutaneous coronary intervention (PCI).



    Product Detail

    Product Tags


    Enoxaparin Sodium
    Source Intestinal mucosa of pigs
    Quality standard






    white or almost white;?hygroscopic powder


    freely soluble in water
    identification The spectra exhibit maxima at 231±2nm The 13C NMR spectrum obtained is similar to that obtained with the appropriate specific Enoxaparin sodium CRS
    The spectra are similar 15 -25 % bearing the 1,6-anhydro structure at the reducing end of their chain
    Anti- Xa activity/?anti-?IIa?: 3.3-5.3 Anti- Xa activity/?anti-?IIa?: 3.3-5.3
    Mw :?3800?-5000Da, M≤2000?:?12.0%-20.0%,???????????????????????????????M≥8000:NMT 18.0%, M2000-8000:68.0%-82.0% Mw :?3800?-5000Da, M≤2000?:?12.0%-20.0%,???????????????????????????????M≥8000:NMT 18.0%, M2000-8000:68.0%-82.0%
    Meets the requirements for Sodium Content It complies with the test for sodium
    Appearance of solution / clear;NMT: intensity?6
    Specific Absorbance 14.0-20.0 (on the dried basis) 14.0-20.0 (on the dried basis),determined at 231nm
    pH 6.2-7.7 6.2-7.7
    Benzyl alcohol ≤?0.1% ≤?0.1%
    Molar ratio of Sulfate carboxylate ≥?1.8 ≥?1.8
    Nitrogen 1.8?%-2.5 %?(on the dried basis) 1.5 %-2.5 %?(on the dried basis)
    Sodium 11.3%?-13.5%?(on the dried basis) 11.3%?-13.5%?(on the dried basis)
    Loss on drying ≤?10.0% ≤?10.0%
    Bacterial endotoxins <0.01EU/U <0.01EU/IU
    Assay Anti- Xa activity 90-125 IU/mg (on the dried basis) 90-125 IU/mg (on the dried basis)
    Anti- IIa activity 20-35 IU/mg (on the dried basis) 20-35 IU/mg (on the dried basis)

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